March 21, 2018

Data suggest that the ideal training stimulus for increasing stem cell quantity involves moderate to high training intensity and frequency using weight-bearing exercise modalities. Another important finding is that the effects of exercise training on stem cell quantity...

March 8, 2018


As we have seen in previous blog posts in this mini-series of obesity and stem cells, there is a chronic low-grade systemic inflammation (metabolic inflammation) in obesity. The proinflammatory condition of obesity is considered the main factor in the patho...

March 1, 2018

Image: Wikipedia


Over the past several blog posts, we have seen the significant negative effects of obesity. There are also differences between genders with regard to obesity; premenopausal women actually have a protection agains obesity compared to men and...

February 22, 2018

Image Source: Mayo Clinic 


An hypothesis was offered roughly a decade ago that osteoporosis might be considered the obesity of the bone.(1) The reason I find this hypothesis so engaging and interesting is that because for years obesity and overweight were co...

February 12, 2018


In this series on the impact of obesity upon stem cells, we have reviewed a bit of data on stem cells (and/or progenitor cells) from various sources and seen that the impact in terms of the numbers of cells and the cellular functions are influenced by obesi...

February 9, 2018


As we saw in Obesity and Stem Cells, Part I, the impact of obesity could be variable depending upon the source of the stem cells. In this particular blog, we will focus upon haematopoietic stem and progenitor cells (HSPCs) in the bone marrow. For this, we a...

February 7, 2018


Obesity is never a fun topic to discuss. In fact, even the discussion of the topic can be associated with "fat shaming." However, ignoring the realities of the effects of obesity is more shameful. Moreover, obesity has a special, and difficult, meaning for...

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