
Regenerative Medicine and Healthcare Innovations: Empirical and Precision Medicine
Regenerative medicine is a healthcare innovation that itself is ready for innovations. Discussed here is how innovations will move this fiel


Exercise and Stem Cells - Part IV, Regenerative Medicine Approaches to Sarcopenia and Muscle Loss
The microenvironment is crucial to successful satellite cell activation as well as repair and regeneration of muscle. Skeletal muscle has an


Exercise and Stem Cells - Part III, Muscle Stem Cells and Mesenchymal-Derived Cells
Exercise training benefits the elderly and the young as well as men and women consistently with regard to stem cells / progenitor cells. Lon


Exercise and Stem Cells - Part II, Haematopoietic Stem, Endothelial Progenitor, and Mesenchymal Stem
This is an important area for future research in order to optimize cell-based therapies for disease. The transient mobilization increase in


Exercise and Stem Cells - Part I, Introduction and Haematopoietic Stem and Progenitor Cells
Data suggest that the ideal training stimulus for increasing stem cell quantity involves moderate to high training intensity and frequency u


Obesity and Stem Cells - Part VI, Obesity, Type 2 Diabetes, and Immune Properties of Human Adipose-D
INTRODUCTION As we have seen in previous blog posts in this mini-series of obesity and stem cells, there is a chronic low-grade systemic inflammation (metabolic inflammation) in obesity. The proinflammatory condition of obesity is considered the main factor in the pathogenesis of insulin resistance, leading to Type 2 diabetes; previous blog posts in this mini-series have discussed some of the association of obesity and Type 2 diabetes, but we haven’t yet discussed their impac

Obesity and Stem Cells - Part V, Cancer
Image: Wikipedia INTRODUCTION Over the past several blog posts, we have seen the significant negative effects of obesity. There are also differences between genders with regard to obesity; premenopausal women actually have a protection agains obesity compared to men and postmenopausal women; leukocyte and haematopoietic stem cells have different responses to obesity and these autonomous differences lead to an amplified response in males compared with females.(1) That is to sa